FITC标记的SH3结构域结合蛋白3抗体
产品名称： FITC标记的SH3结构域结合蛋白3抗体
英文名称： Anti-SH3BP1/FITC
产品编号： HZ-19748R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SH3BP1/FITC Conjugated antibody
FITC标记的SH3结构域结合蛋白3抗体
| 英文名称 | Anti-SH3BP1/FITC |
| 中文名称 | FITC标记的SH3结构域结合蛋白3抗体 |
| 别 名 | 3BP 1; 3BP-1; 3BP1_HUMAN; ARHGAP43; dJ37E16; SH3 domain binding protein 1; SH3 domain-binding protein 1; Sh3bp1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 76kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SH3BP1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | Function: Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac. Similarity: Contains 1 BAR domain. Contains 1 Rho-GAP domain. Database links: Entrez Gene: 23616 Human Entrez Gene: 20401 Mouse Entrez Gene: 300067 Rat SwissProt: Q9Y3L3 Human SwissProt: P55194 Mouse Unigene: 601143 Human Unigene: 4462 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
与信号转导途径中某些蛋白质的SH3结构域有差异。该蛋白优先与ABL1原癌基因、Src和Grb2结合。显示Rac相关蛋白的间隙活性，而不是Rho或RAS相关蛋白。它抑制PDGF诱导的RAGE介导的膜皱褶。