Product: Anti-ILPIP (Internal) pAb
Cat. No.: PC-442 (100 μg)
Synonyms:
PAPK, ALSCR2.
Description:
ILPIP (ILP-interacting protein) has recently been
shown to interact with XIAP, a member of the
IAP (Inhibitor of Apoptosis) protein family.
Together, these two proteins synergistically
activate the TAK1/JNK1 signal transduction
pathway, which acts to protect against the
interleukin-1
converting enzyme of Fas-induced
apotosis. This protein was independently
isolated and characterized as polyploidyassociated
protein kinase (PAPK), a member of
the Ste20/germinal center kinase family that
modulates cytoskeletal organization and cell
survival, suggesting that its protective role may
be a function of its kinase activity. Although two
mRNA sequences have been isolated, only the
shorter isoform has been observed.
Specificity:
Recognizes ILPIP.
Species Reactivity:
Human, mouse and rat.
Host:
Rabbit
Immunogen:
Anti-ILPIP polyclonal antibody was raised
against a peptide corresponding to amino acids
near the center of human ILPIP (GenBank
accession no. NP_061041).
Positive Control:
Human brain cell lysate can be used. A 34 kDa
band can be detected.
Format:
100 μg of immunoaffinity-purified IgG in PBS
containing 0.02 sodium azide.
Storage:
Store at 4°C.
Applications:

Western blot: Recommend 1 - 2 μg/mL.
The optimal dilution for a specific application
should be determined by the researcher.
Limitations:
For in vitro research use only. Not for use in
diagnostics or in humans.
Warranty:
No warranties, expressed or implied, are made
regarding the use of this product. KAMIYA
BIOMEDICAL COMPANY is not liable for any
damage, personal injury, or economic loss
caused by this product.