DHX16,ATP-依赖的RNA解旋酶3抗体

产品编号HZ-14311R
英文名称DHX16
中文名称ATP-依赖的RNA解旋酶3抗体
别 名2410006N22Rik; ATP-dependent RNA helicase #3; ATP-dependent RNA helicase 3; DAQB-47P19.12; DBP 2; DBP2; DDX 16; DDX16; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16; DEAD/H box 16; DEAH (Asp-Glu-Ala-His) box polypeptide 16; DEAH box protein 16; DEAH box protein; DEAH-box protein 16; DEAH-box protein; DHX16; DHX16_HUMAN; fa91b12; KIAA0577; mKIAA0577; PRO2014; PRP 8; Prp2; PRP8; PRPF2; Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; RNA helicase; wu:fa91b12; zgc:55590.
说 明 书0.1ml 0.2ml
研究领域细胞生物 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
DHX16,ATP-依赖的RNA解旋酶3抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量119kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DHX16
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DHX16,ATP-依赖的RNA解旋酶3抗体PubMedPubMed
产品介绍background:
DDX16 is a 1,041 amino acid protein that contains one helicase ATP-binding domain and one helicase C-terminal domain. One of several members of the DEAD-box protein family, DDX16 localizes to the nucleus and is thought to function as an RNA helicase that is involved in pre-mRNA splicing events, playing an important role in cell cycle progression. The gene encoding DDX16 is located on a region of chromosome 6 that is associated with a variety of diseases, including malignancies and genetic mutations, suggesting a possible role for DDX16 in the pathogenesis of certain disorders.

Function:
Probable ATP-binding RNA helicase involved in pre-mRNA splicing.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.

Gene ID:
8449

Database links:
Entrez Gene: 8449 Human
Entrez Gene: 100719266 Human
Entrez Gene: 506405 Cow
Entrez Gene: 713836 Human
Entrez Gene: 69192 Mouse
Entrez Gene: 100144456 Pig
Entrez Gene: 294232 Rat
Entrez Gene: 336645 Zebrafish
Omim: 603405 Human
SwissProt: O60231 Human
SwissProt: Q767K6 Pig
Unigene: 485060 Human

DHX16,ATP-依赖的RNA解旋酶3抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.