FITC标记的KNCN蛋白抗体
产品名称： FITC标记的KNCN蛋白抗体
英文名称： Anti-KNCN/FITC
产品编号： HZ-16800R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-KNCN/FITC Conjugated antibody
FITC标记的KNCN蛋白抗体
| 英文名称 | Anti-KNCN/FITC |
| 中文名称 | FITC标记的KNCN蛋白抗体 |
| 别 名 | FLJ32011; Kino; Kinocilin; Kncn; KNCN_HUMAN; L5; RP11-49P4.2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 13kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KNCN |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Kinocilin is a 124 amino acid multi-pass membrane protein that may play a role in the stabilization of dense microtubular networks, and may also participate in vesicular trafficking. Existing as two alternatively spliced isoforms, the gene encoding Kinocilin maps to human chromosome 1p33 and mouse chromosome 4 D1. Chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. A large number of disease-associated genes are present on chromosome 1, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. Function: May plays a role in stabilizing dense microtubular networks or in vesicular trafficking. Subcellular Location: Membrane. Database links: Entrez Gene: 148930 Human Omim: 611455 Human SwissProt: A6PVL3 Human Unigene: 350764 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Kinocilin是一种124个氨基酸的多路膜蛋白，在致密微管网络的稳定中可能起作用，也可能参与囊泡运输。Kinocilin基因以两种可选择的剪接异构体存在，编码Kinocilin的基因定位于人染色体1p33和小鼠染色体4D1。第1号染色体跨越2亿6000万个碱基对，包含超过3000个基因，并包含人类基因组的近8%。染色体1上存在大量的疾病相关基因，包括家族性腺瘤性息肉病、Stickler综合征、帕金森病、Gaucher病、精神分裂症和Usher综合征。染色体1异常存在于各种癌症中，包括头颈癌、恶性黑色素瘤和多发性骨髓瘤。