FITC标记的乳腺上皮细胞抗原BA46抗体
产品名称： FITC标记的乳腺上皮细胞抗原BA46抗体
英文名称： Anti-MFGE8/BA46/FITC
产品编号： HZ-6454R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-MFGE8/BA46/FITC Conjugated antibody
FITC标记的乳腺上皮细胞抗原BA46抗体
| 产品编号 | bs-6454R-FITC |
| 英文名称 | Anti-MFGE8/BA46/FITC |
| 中文名称 | FITC标记的乳腺上皮细胞抗原BA46抗体 |
| 别 名 | BA46; Breast epithelial antigen BA46; Contains Medin; HMFG; Lactadherin [Precursor]; Lactadherin; Medin; MFG E8; MFG-E8; MFGE8; MFGM; MFGM_HUMAN; Milk fat globule EGF factor 8; Milk fat globule EGF factor 8 protein; Milk fat globule-EGF factor 8; O acetyl disialoganglioside synthase; OAcGD3S; SED1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 细胞生物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 5.5/20/40kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MFGE8/BA46 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication. Medin is the main constituent of aortic medial amyloid. Function: Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication. Subcellular Location: Membrane. Secreted. Tissue Specificity: Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas. Post-translational modifications: Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273. Similarity: Contains 1 EGF-like domain. Contains 2 F5/8 type C domains. Database links: Entrez Gene: 4240 Human Entrez Gene: 17304 Mouse Entrez Gene: 25277 Rat Omim: 602281 Human SwissProt: Q08431 Human SwissProt: P21956 Mouse SwissProt: P70490 Rat Unigene: 3745 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
在维持肠上皮内稳态和促进粘膜愈合中起重要作用。促进血管内皮生长因子依赖的新生血管（通过相似性）。有助于吞噬许多组织中的凋亡细胞。α-V/BETA-3和α-V/BETA－5受体的特异性配体。还以受体独立的方式结合磷脂酰丝氨酸富集的细胞表面。Zona pellucida结合蛋白可能参与配子的相互作用。特异性结合轮状病毒并抑制其复制。Mein是主动脉内淀粉样蛋白的主要成分。